Isn’t it great just to swallow a pill and get slim! Dutch pharmacists came up with new remedy against excessive weight. Scientists claim their weight loss pill (tesofensine) is twice as effective as current slimming pills. The remedy helps control your appetite and, as a result, allows you to lose two sizes in six months.
Surprising Weight Loss Drug
A new drug’s effect is based on the suppression of nervous system mediators responsible for appetite – serotonin, dopamine and noradrenaline. As a result, hunger pangs are subdued and we need smaller portions to feel full. Originally, the drug was developed to treat Parkinson’s and Alzheimer’s diseases. But scientists noticed its ability to cause weight loss.
The Weight Loss Study
The study led by Professor Arne Astrup involved 203 obese adults with the average weight of 220 pounds. All participants were asked to diet and to take one pill per day for six months. Approximately equal number of participants received either tesofensine in one of three different doses or placebo pill.
The Effect of Tesofensine
Six months later, participants who took placebo pills lost 5 pounds on average. Those who took tesofensine in the dose of 0.25 mg, 0.5 mg and 1 mg lost 15, 25 and 28 pounds respectively. Last two figures show that tesofensine is twice as effective as current weight loss drugs, such as sibutramine and rimonabant.
Third phase of clinical trials is on the way. If final trials are successful, tesofensine might hit the stores in a few years.